Wnt won the war: Antagonistic role of Wnt over Shh controls dorso‐ventral patterning of the vertebrate neural tube

@article{Ulloa2010WntWT,
  title={Wnt won the war: Antagonistic role of Wnt over Shh controls dorso‐ventral patterning of the vertebrate neural tube},
  author={Fausto Ulloa and Elisa Mart{\'i}},
  journal={Developmental Dynamics},
  year={2010},
  volume={239}
}
The spinal cord has been used as a model to dissect the mechanisms that govern the patterning of tissues during animal development, since the principles that rule the dorso‐ventral patterning of the neural tube are applicable to other systems. Signals that determine the dorso‐ventral axis of the spinal cord include Sonic hedgehog (Shh), acting as a bona fide morphogenetic signal to determine ventral progenitor identities, and members of the Bmp and the Wnt families, acting in the dorsal neural… Expand
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