Wnt signalling in kidney diseases: dual roles in renal injury and repair.

@article{Kawakami2013WntSI,
  title={Wnt signalling in kidney diseases: dual roles in renal injury and repair.},
  author={Takahisa Kawakami and Shuyu Ren and Jeremy S. Duffield},
  journal={The Journal of pathology},
  year={2013},
  volume={229 2},
  pages={
          221-31
        }
}
Wnt signalling is a complex, highly conserved, cell-to-cell communication pathway in multicellular organisms, regulating cell fate, function and phenotype in development, and diseases, including neoplasia. Although the critical role of the Wnt pathway in nephrogenesis is well established, recent investigations have shown its involvement in many adult kidney diseases, including ischaemic kidney injury, glomerular diseases, diabetic nephropathy, interstitial fibrosis and cystic kidney diseases… CONTINUE READING

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