Wnt signaling regulates homeostasis of the periodontal ligament.

  title={Wnt signaling regulates homeostasis of the periodontal ligament.},
  author={Won Hee Lim and B Liu and Du Cheng and Bart O. Williams and Stephanie J Mah and J A Helms},
  journal={Journal of periodontal research},
  volume={49 6},
BACKGROUND AND OBJECTIVE In health, the periodontal ligament maintains a constant width throughout an organism's lifetime. The molecular signals responsible for maintaining homeostatic control over the periodontal ligament are unknown. The purpose of this study was to investigate the role of Wnt signaling in this process by removing an essential chaperone protein, Wntless (Wls), from odontoblasts and cementoblasts, and observing the effects of Wnt depletion on cells of the periodontal complex… CONTINUE READING
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