Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs.

@article{Ricken2002WntSI,
  title={Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs.},
  author={Albert M. Ricken and Paul Lochhead and Maria Kontogiannea and Riaz Farookhi},
  journal={Endocrinology},
  year={2002},
  volume={143 7},
  pages={
          2741-9
        }
}
Ovarian cadherins, in addition to acting as structural (adhesion) molecules, also function as modulators of gene activity. The dual role of beta-catenin as an intracellular component of the cadherin adhesion complex and as a transcription factor provides a possible explanation for these cadherin effects. Because the transcriptional activity of beta-catenin is dependent on activation by the wnt signaling cascade, we examined whether components of this cascade are expressed in the rat ovary… CONTINUE READING

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