Wnt-responsive Lgr5⁺ globose basal cells function as multipotent olfactory epithelium progenitor cells.

Abstract

Persistent neurogenesis in the olfactory epithelium provides a unique model to study neural stem cell self-renewal and fate determination. In the olfactory neuroepithelium, globose basal cells (GBCs) are considered to be the direct progenitors of olfactory neurons. However, the study of neurogenesis from GBCs has been impeded by the paucity of GBC-specific… (More)
DOI: 10.1523/JNEUROSCI.0240-14.2014

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