Wnt lipidation: Roles in trafficking, modulation, and function

  title={Wnt lipidation: Roles in trafficking, modulation, and function},
  author={Vahid Hosseini and Christian Dani and Mohammad Hossein Geranmayeh and Fatemeh Mohammadzadeh and Saeed Nazari Soltan Ahmad and Masoud Darabi},
  journal={Journal of Cellular Physiology},
  pages={8040 - 8054}
The Wnt signaling pathway consists of various downstream target proteins that have substantial roles in mammalian cell proliferation, differentiation, and development. Its aberrant activity can lead to uncontrolled proliferation and tumorigenesis. The posttranslational connection of fatty acyl chains to Wnt proteins provides the unique capacity for regulation of Wnt activity. In spite of the past belief that Wnt molecules are subject to dual acylation, it has been shown that these proteins have… 
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