Wnt genes and endocrine disruption of the female reproductive tract: a genetic approach.

@article{Sassoon1999WntGA,
  title={Wnt genes and endocrine disruption of the female reproductive tract: a genetic approach.},
  author={David A Sassoon},
  journal={Molecular and cellular endocrinology},
  year={1999},
  volume={158 1-2},
  pages={1-5}
}
Reproductive tract development and function is regulated by circulating steroid hormones. In the mammalian female reproductive tract, estrogenic compounds direct many aspects of cytodifferentiation including uterine gland formation, smooth muscle morphology, and epithelial differentiation. While it is clear that these hormones act through their cognate nuclear receptors, it is less clear what signaling events follow hormonal stimulation that govern cytodifferentiation. Recent advances in… CONTINUE READING

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