Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding

@article{Ito2007WntdependentDN,
  title={Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding},
  author={Mayumi Ito and Zaixin Yang and Thomas Andl and Chunhua Cui and Noori Kim and Sarah E. Millar and George Cotsarelis},
  journal={Nature},
  year={2007},
  volume={447},
  pages={316-320}
}
The mammalian hair follicle is a complex ‘mini-organ’ thought to form only during development; loss of an adult follicle is considered permanent. However, the possibility that hair follicles develop de novo following wounding was raised in studies on rabbits, mice and even humans fifty years ago. Subsequently, these observations were generally discounted because definitive evidence for follicular neogenesis was not presented. Here we show that, after wounding, hair follicles form de novo in… 

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