Wnt and TGFbeta signals subdivide the AbdA Hox domain during Drosophila mesoderm patterning.

@article{Bilder1998WntAT,
  title={Wnt and TGFbeta signals subdivide the AbdA Hox domain during Drosophila mesoderm patterning.},
  author={David Bilder and Yacine Graba and Matthew P Scott},
  journal={Development},
  year={1998},
  volume={125 9},
  pages={
          1781-90
        }
}
Hox genes have large expression domains yet control the formation of fine pattern elements at specific locations. We have examined the mechanism underlying subdivision of the abdominal-A (abdA) Hox domain in the visceral mesoderm. AbdA directs formation of an embryonic midgut constriction at a precise location within the broad and uniform abdA expression domain. The constriction divides the abdA domain of the midgut into two chambers, the anterior one producing the Pointed (Pnt) ETS… CONTINUE READING

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