Wnt/Wingless signaling in Drosophila.

@article{Swarup2012WntWinglessSI,
  title={Wnt/Wingless signaling in Drosophila.},
  author={Sharan Swarup and Esther M Verheyen},
  journal={Cold Spring Harbor perspectives in biology},
  year={2012},
  volume={4 6}
}
The Wingless (Wg) pathway represents one of the best-characterized intercellular signaling networks. Studies performed in Drosophila over the last 30 years have contributed to our understanding of the role of Wg signaling in the regulation of tissue growth, polarity, and patterning. These studies have revealed mechanisms conserved in the vertebrate Wnt pathways and illustrate the elegance of using the Drosophila model to understand evolutionarily conserved modes of gene regulation. In this… CONTINUE READING
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