Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling.

Abstract

Wnt/β-catenin signalling is central to development and its regulation is essential in preventing cancer. Using phosphorylation of Dishevelled as readout of pathway activation, we identified Drosophila Wnk kinase as a new regulator of canonical Wnt/β-catenin signalling. WNK kinases are known for regulating ion co-transporters associated with hypertension… (More)
DOI: 10.1038/embor.2013.88

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@article{Serysheva2013WnkKA, title={Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling.}, author={Ekatherina Serysheva and Hebist Berhane and Luca Grumolato and Kubilay Demir and Sophie Balmer and Maxime Bodak and Michael Boutros and Stuart Aaronson and Marek Mlodzik and Andreas Jenny}, journal={EMBO reports}, year={2013}, volume={14 8}, pages={718-25} }