Withdrawing Benzodiazepines in Primary Care

  title={Withdrawing Benzodiazepines in Primary Care},
  author={Malcolm Harold Lader and Andr{\'e} T. Tylee and John Donoghue},
  journal={CNS Drugs},
The use of benzodiazepine anxiolytics and hypnotics continues to excite controversy. Views differ from expert to expert and from country to country as to the extent of the problem, or even whether long-term benzodiazepine use actually constitutes a problem. The adverse effects of these drugs have been extensively documented and their effectiveness is being increasingly questioned. Discontinuation is usually beneficial as it is followed by improved psychomotor and cognitive functioning… 

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It is concluded that little evidence exists outside the usual principles of drug withdrawal but there are some promising leads.

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The benzodiazepines (BZDs) are anxiolytics, hypnotics, anticonvulsants, muscle‐relaxants and induce anaesthesia. Adverse effects comprise sedation subjectively and cognitive and psychomotor

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Since the first benzodiazepines were marketed in the late 1950s, their use has steadily increased, culminating in one benzodiazepine, diazepam, being one of the most widely prescribed drugs of all

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Since the first benzodiazepines were marketed in the late 1950s, their use has steadily increased, culminating in one benzodiazepine, diazepam, being one of the most widely prescribed drugs of all

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    Current opinion in psychiatry
  • 2005
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  • Psychology, Medicine
    Journal of clinical psychopharmacology
  • 1999
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  • Medicine
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