Withdrawal syndrome following cessation of antihypertensive drug therapy

@article{Karachalios2005WithdrawalSF,
  title={Withdrawal syndrome following cessation of antihypertensive drug therapy},
  author={George N. Karachalios and Alexandros Charalabopoulos and Vicky Papalimneou and D. N. Kiortsis and P Dimicco and O. K. Kostoula and K. Charalabopoulos},
  journal={International Journal of Clinical Practice},
  year={2005},
  volume={59}
}
In this study, a review of the available information concerning abrupt withdrawal of antihypertensive drug therapy is presented. Abrupt withdrawal of these drugs can produce a syndrome of sympathetic overactivity that includes nervousness, tachycardia, headache, agitation and nausea 36–72 h after cessation of the drug. A withdrawal syndrome may occur after discontinuation of almost all types of antihypertensive drugs, but mostly occurs with clonidine, β‐blockers, methyldopa and guanabenz. Less… 

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