Withania somnifera shows a protective effect in monocrotaline-induced pulmonary hypertension.

@article{Kaur2015WithaniaSS,
  title={Withania somnifera shows a protective effect in monocrotaline-induced pulmonary hypertension.},
  author={Gurpreet Kaur and Neetu Singh and Sheeba Saji Samuel and Himangshu Kousik Bora and Sharad K Sharma and Shakti Deep Pachauri and Anil Kumar Dhar Dwivedi and Hefazat Hussain Siddiqui and Kashif Hanif},
  journal={Pharmaceutical biology},
  year={2015},
  volume={53 1},
  pages={
          147-57
        }
}
CONTEXT Withania somnifera (Linn.) Dunal (Solanaceae), a clinically used herbal drug in Ayurveda, shows potent antioxidant, anti-inflammatory, pro-apoptotic, and cardioprotective effects. However, the efficacy of W. somnifera in pulmonary hypertension (PH), a cardiopulmonary disorder, remains unexplored. OBJECTIVE The present study investigates the effect of W. somnifera root powder on monocrotaline (MCT)-induced PH in rats. MATERIALS AND METHODS In preventive studies, W. somnifera root… CONTINUE READING
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