Withaferin A Inhibits STAT3 and Induces Tumor Cell Death in Neuroblastoma and Multiple Myeloma

@inproceedings{Yco2014WithaferinAI,
  title={Withaferin A Inhibits STAT3 and Induces Tumor Cell Death in Neuroblastoma and Multiple Myeloma},
  author={Lisette P. Yco and Gabor Mocz and John Opoku-Ansah and Andr{\'e} S Bachmann},
  booktitle={Biochemistry insights},
  year={2014}
}
Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that has been implicated in many human cancers and has emerged as an ideal target for cancer therapy. Withaferin A (WFA) is a natural product with promising antiproliferative properties through its association with a number of molecular targets including STAT3. However, the effect of WFA in pediatric neuroblastoma (NB) and its interaction with STAT3 have not been reported. In this study, we found… CONTINUE READING
Tweets
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-3 of 3 citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references