Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells.

@article{Salle2004WindowsFS,
  title={Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells.},
  author={S. La Salle and C. Mertineit and T. Taketo and P. Moens and T. Bestor and J. Trasler},
  journal={Developmental biology},
  year={2004},
  volume={268 2},
  pages={
          403-15
        }
}
The acquisition of genomic methylation in the male germ line is initiated prenatally in diploid gonocytes, while DNA methylation in the female germ line is initiated postnatally in growing oocytes. We compared the temporal expression patterns of the DNA methyltransferases, DNMT1, DNMT3a, DNMT3b, and DNMT3l in the male and female germ lines. DNMT1 expression was examined by immunocytochemistry and Northerns with an emphasis on the prenatal period. In the female, there is a gradual down… Expand
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