Wilson’s Disease: A Comprehensive Review of the Molecular Mechanisms

  title={Wilson’s Disease: A Comprehensive Review of the Molecular Mechanisms},
  author={Fei Wu and Jing Wang and Chunwen Pu and Liang Qiao and Chunmeng Jiang},
  booktitle={International journal of molecular sciences},
Wilson's disease (WD), also known as hepatolenticular degeneration, is an autosomal recessive inherited disorder resulting from abnormal copper metabolism. Reduced copper excretion causes an excessive deposition of the copper in many organs such as the liver, central nervous system (CNS), cornea, kidney, joints, and cardiac muscle where the physiological functions of the affected organs are impaired. The underlying molecular mechanisms for WD have been extensively studied. It is now believed… CONTINUE READING
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