Wilms tumors: relationship of nuclear deoxyribonucleic acid ploidy to patient survival.

@article{Rainwater1987WilmsTR,
  title={Wilms tumors: relationship of nuclear deoxyribonucleic acid ploidy to patient survival.},
  author={Leslie M. Rainwater and Yoshio Hosaka and George M. Farrow and Stephen A. Kramer and Panayotis P. Kelalis and Michael M. Lieber},
  journal={The Journal of urology},
  year={1987},
  volume={138 4 Pt 2},
  pages={
          974-7
        }
}
Nuclear deoxyribonucleic acid ploidy studies with paraffin-embedded archival tumor specimens were performed by flow cytometry on extracted nuclei from 56 Wilms tumors. Before the era of chemotherapy 9 patients had a 33 per cent survival rate at 5 years. No significant correlation between deoxyribonucleic acid ploidy pattern and survival was seen in this early group of patients. Since 1960, 47 patients underwent radical nephrectomy and received chemotherapy. Deoxyribonucleic acid histograms in… CONTINUE READING