Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells.

@article{Hostanska2007WillowBE,
  title={Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells.},
  author={Katarina Hostanska and Guido Juergenliemk and Gudrun Abel and Adolf Nahrstedt and Reinhard Saller},
  journal={Cancer detection and prevention},
  year={2007},
  volume={31 2},
  pages={129-39}
}
BACKGROUND Recently, there have been extensive efforts to evaluate the chemopreventive role of substances present in natural products. The aim of this study was to examine the effects of the main groups of compounds (salicylalcohol derivates, flavonoids, proanthocyanidins), and salicin isolated from willow bark extract BNO 1455 on proliferation and apoptosis in human colon and cancer cells. METHODS We used human colon cyclooxygenase-2 (COX-2)-positive HT 29 and (COX-2)-negative HCT 116 or… CONTINUE READING
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