Will the new CB1 cannabinoid receptor antagonist SR-147778 have advantages over rimonabant?

@article{Doggrell2005WillTN,
  title={Will the new CB1 cannabinoid receptor antagonist SR-147778 have advantages over rimonabant?},
  author={Sheila Anne Doggrell},
  journal={Expert Opinion on Investigational Drugs},
  year={2005},
  volume={14},
  pages={339 - 342}
}
  • S. Doggrell
  • Published 1 March 2005
  • Medicine
  • Expert Opinion on Investigational Drugs
Obesity and alcoholism are two common modern-day diseases. The cannabinoid CB1 receptor antagonist rimonabant is in Phase III clinical trial for the treatment of obesity with preliminary results showing that it decreases appetite and body weight. Animal studies have shown that rimonabant is effective in the treatment of alcoholism. SR-147778 is a new potent and selective CB1 receptor antagonist. In animals, SR-147778 has been shown to inhibit CB1 receptor-mediated hypothermia, analgesia and… 
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