Corpus ID: 14402653

Will There Ever Be An Accurate Test for Lyme Disease?

  title={Will There Ever Be An Accurate Test for Lyme Disease?},
  author={T. Grier},
Lyme Disease is a complex systemic disease that is caused by highly motile bacterium in the spirochete family. The bacteria Borrelia burgdorferi was first isolated from the skin of a Lyme patient with the distinctive bull’s-eye rash in the early 1980s. Since that time, culturing the elusive bacterium has been difficult, frustratingly unpredictable, and miserably inconsistent. Borrelia burgdorferi can very quickly move from the site of a tick bite into the circulatory system, where it can… Expand


Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy.
Lyme borreliosis (or Lyme disease) is a systemic disorder caused by the spirochete Borrelia burgdorferi, a newly discovered species of bor RELIA, which is transmitted by arthropod species. Expand
Spirochetes in the spleen of a patient with chronic Lyme disease.
A 54-year-old man had intermittent evening fever, arthralgia, transient erythematous macular eruption on the skin, and splenomegaly of two year's duration, consistent with persistence of B. burgdorferi organisms in inner organs in chronic Lyme disease. Expand
Demonstration of spirochetes in cardiac biopsies of patients with Lyme disease.
Cardiac involvement occurring early in Borrelia burgdorferi infection is a clinical manifestation of human Lyme disease and permanent heart damage may result from cardiac involvement in Lyme disease. Expand
Survival of Borrelia burgdorferi in antibiotically treated patients with lyme borreliosis
It is concluded that early stage of the disease as well as chronic Lyme disease with persistence of Borrelia burgdorferi after antibiotic therapy cannot be excluded when the serum is negative for antibodies against B. burgdorFERi. Expand
Seronegative chronic relapsing neuroborreliosis.
An unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy was associated with a Jarisch-Herxheimer-like reaction. Expand
Interlaboratory comparison of test results for detection of Lyme disease by 516 participants in the Wisconsin State Laboratory of Hygiene/College of American Pathologists Proficiency Testing Program
Strong criteria must be applied for approving and continuing to approve commercially available kits for the serodiagnosis of Lyme disease, according to the case definition of the Centers for Disease Control and Prevention. Expand
Cultivation of Bb from Joint Fluid Three Months After Treatment of Facial Palsy Due to Lyme Borreliosis
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Repeated Isolation of Spirochetes From the Cerebrospinal Fluid of an Antibiotic-treated Patient with Meningoradiculitis Bannwarth’ Syndrome
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