Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle.

@article{Critchley2002WildtypeER,
  title={Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle.},
  author={Hilary O D Critchley and Teresa A Henderson and Rodney W. Kelly and Graeme S Scobie and Lee R Evans and Nigel Patrick Groome and Philippa T K Saunders},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2002},
  volume={87 11},
  pages={5265-73}
}
Estrogen action is mediated via two subtypes of the estrogen receptor (ER), usually referred to as ERalpha and ERbeta. We have previously compared the spatial and temporal expressions of ERalpha and ERbeta proteins in human endometrium and reported that endothelial cells exclusively express ERbeta. In the present study we have extended our investigations to compare the pattern of expression of wild-type (ERbeta1) and a newly identified ERbeta variant isoform (ERbetacx/beta2) that lacks the… CONTINUE READING
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