Wild isolates of Plasmodium falciparum malaria show decreased sensitivity to in vitro inhibition of parasite growth mediated by autologous host antibodies.

@article{Flyg1997WildIO,
  title={Wild isolates of Plasmodium falciparum malaria show decreased sensitivity to in vitro inhibition of parasite growth mediated by autologous host antibodies.},
  author={B. W{\aa}hlin Flyg and Hedvig Perlmann and Peter Perlmann and F. Esposito and Klavs Berzins},
  journal={Clinical and experimental immunology},
  year={1997},
  volume={107 2},
  pages={321-7}
}
Antigenic diversity in field populations of Plasmodium falciparum parasites may delay the acquisition of protective immunity to malaria, the development of which may thus require repeated exposure to infection over a prolonged period of time. In this study we show that P. falciparum parasites may vary in their sensitivity to antibody-mediated invasion/growth inhibition in vitro. Wild isolates of P. falciparum from children living in an endemic area of Burkina Faso were tested for their… CONTINUE READING