Wild Panax ginseng (Panax ginseng C.A. Meyer) protects against methotrexate-induced cell regression by enhancing the immune response in RAW 264.7 macrophages.

@article{Jang2010WildPG,
  title={Wild Panax ginseng (Panax ginseng C.A. Meyer) protects against methotrexate-induced cell regression by enhancing the immune response in RAW 264.7 macrophages.},
  author={Hyo Il Jang and H. Shin},
  journal={The American journal of Chinese medicine},
  year={2010},
  volume={38 5},
  pages={
          949-60
        }
}
  • Hyo Il Jang, H. Shin
  • Published 2010
  • Biology, Medicine
  • The American journal of Chinese medicine
Many traditional herbal medicines have been re-evaluated to determine whether they enhance immune responses. In this study, the possible use of wild Panax ginseng (WPG) for enhancement of host immunity in chemotherapy was investigated. In the cell proliferation assay, WPG significantly enhanced the proliferation of RAW 264.7 macrophages and protected against cell regression in macrophages treated with methotrexate (MTX). WPG induced the production of nitric oxide and the expression of inducible… Expand
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