Wild Argentinian Amaryllidaceae, a New Renewable Source of the Acetylcholinesterase Inhibitor Galanthamine and Other Alkaloids

@article{Ortiz2012WildAA,
  title={Wild Argentinian Amaryllidaceae, a New Renewable Source of the Acetylcholinesterase Inhibitor Galanthamine and Other Alkaloids},
  author={Javier E. Ortiz and S. Berkov and Natalia B. Pigni and C. Theoduloz and G. Roitman and A. Tapia and J. Bastida and G. Feresin},
  journal={Molecules},
  year={2012},
  volume={17},
  pages={13473 - 13482}
}
The Amaryllidaceae family is well known for its pharmacologically active alkaloids. An important approach to treat Alzheimer’s disease involves the inhibition of the enzyme acetylcholinesterase (AChE). Galanthamine, an Amaryllidaceae alkaloid, is an effective, selective, reversible, and competitive AChE inhibitor. This work was aimed at studying the alkaloid composition of four wild Argentinian Amarillydaceae species for the first time, as well as analyzing their inhibitory activity on… Expand
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