Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides.

@article{Boorse2006WidespreadTD,
  title={Widespread tissue distribution and diverse functions of corticotropin-releasing factor and related peptides.},
  author={Graham C. Boorse and Robert J Denver},
  journal={General and comparative endocrinology},
  year={2006},
  volume={146 1},
  pages={9-18}
}
Peptides of the corticotropin-releasing factor (CRF) family are expressed throughout the central nervous system (CNS) and in peripheral tissues where they play diverse roles in physiology, behavior, and development. Current data supports the existence of four paralogous genes in vertebrates that encode CRF, urocortin/urotensin 1, urocortin 2 or urocortin 3… CONTINUE READING