Widespread structural brain changes in OCD: A systematic review of voxel-based morphometry studies
@article{Piras2015WidespreadSB, title={Widespread structural brain changes in OCD: A systematic review of voxel-based morphometry studies}, author={Federica Piras and Fabrizio Piras and Chiara Chiapponi and Paolo Girardi and Carlo Caltagirone and Gianfranco Spalletta}, journal={Cortex}, year={2015}, volume={62}, pages={89-108} }
154 Citations
Brain circuitries of obsessive compulsive disorder: A systematic review and meta-analysis of diffusion tensor imaging studies
- Psychology, BiologyNeuroscience & Biobehavioral Reviews
- 2013
Obsessive-compulsive disorder is a heterogeneous disorder: evidence from diffusion tensor imaging and magnetization transfer imaging
- Psychology, BiologyBMC Psychiatry
- 2015
The hypothesis that OCD is a heterogeneous disorder with distinct neural correlates across symptom dimensions is supported and a substantial revision of such a model that takes into account the heterogeneity of the disorder is called for.
Morphological brain alterations in patients with obsessive–Compulsive disorder
- Psychology, Biology
- 2018
The reviewed literature shows that the pathophysiology of OCD cannot be explained by alterations in function and structure of the classical CSTC regions exclusively and emphasizes the importance of other fronto-limbic and frontoparietal areas as well as the cerebellum.
Functional Connectivity of the Striatum as a Neural Correlate of Symptom Severity in Patient with Obsessive-Compulsive Disorder
- Psychology, BiologyPsychiatry investigation
- 2020
Striatal subregions have strengthened FC with extensive cortical regions, which may reflect neural correlates of compulsive and anxious symptoms in OCD patients, and contribute to an improved understanding of OCD pathophysiology.
Cortico-striato-thalamo-cortical circuit abnormalities in obsessive-compulsive disorder: A voxel-based morphometric and fMRI study of the whole brain
- Psychology, BiologyBehavioural Brain Research
- 2016
Alterations of gray and white matter morphology in obsessive compulsive disorder.
- Psychology, MedicinePsicothema
- 2017
Structural alterations in both white and gray matter in a sample of OCD patients when compared with a group of non-clinical matched controls are tested using voxel-based morphometry (VBM), finding alterations may be associated with prominent OCD symptoms.
Cerebellar volume deficits in medication-naïve obsessive compulsive disorder
- Psychology, BiologyPsychiatry Research: Neuroimaging
- 2016
Relationship between symptom dimensions and brain morphology in obsessive-compulsive disorder
- PsychologyBrain Imaging and Behavior
- 2016
It is indicated that there were specific brain regions in gray and white matter that contributed to symptom dimensions in OCD patients, and this result was preliminary.
Gray Matter Alterations in Pediatric Schizophrenia and Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis of Voxel-Based Morphometry Studies
- Psychology, MedicineFrontiers in Psychiatry
- 2022
The results suggest that gray matter abnormalities in the PFC may indicate homogeneity between the two diseases, and in children and adolescents, structural alterations in schizophrenia mainly involve the fronto-temporal and cortico-insula circuits, whereas those in OCD mainly involveThe prefrontal-parietal and the prefrontal-striatal circuits.
Abnormal white matter structural connectivity in adults with obsessive-compulsive disorder
- PsychologyTranslational Psychiatry
- 2017
Novel evidence of widespread microstructural alterations in OCD is provided and it is suggested that OCD may involve abnormalities affecting a broader network of regions than commonly believed.
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