Widespread release of peptides in the central nervous system: quantitation of tannic acid-captured exocytoses.

@article{Morris1991WidespreadRO,
  title={Widespread release of peptides in the central nervous system: quantitation of tannic acid-captured exocytoses.},
  author={John Frederick Morris and David V. Pow},
  journal={The Anatomical record},
  year={1991},
  volume={231 4},
  pages={
          437-45
        }
}
Tannic acid methods have been applied to capture the exocytosis of peptide-containing granules from peptidergic neurons. The captured exocytoses have been quantitated to assess the proportion and amount of peptide released at different parts of the neuronal membrane. Examination of hypothalamic synaptic boutons shows that only about one-half of the peptidergic vesicles is exocytosed into the synaptic cleft and also that exocytosis also occurs from undilated peptidergic axons. Study of the… CONTINUE READING
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