Widespread genetic incompatibility in C. elegans maintained by balancing selection.

@article{Seidel2008WidespreadGI,
  title={Widespread genetic incompatibility in C. elegans maintained by balancing selection.},
  author={Hannah S. Seidel and Matthew V Rockman and Leonid Kruglyak},
  journal={Science},
  year={2008},
  volume={319 5863},
  pages={589-94}
}
Natural selection is expected to eliminate genetic incompatibilities from interbreeding populations. We have discovered a globally distributed incompatibility in the primarily selfing species Caenorhabditis elegans that has been maintained despite its negative consequences for fitness. Embryos homozygous for a naturally occurring deletion of the zygotically acting gene zeel-1 arrest if their sperm parent carries an incompatible allele of a second, paternal-effect locus, peel-1. The two… CONTINUE READING
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