Widespread expression of MyoD genes in Xenopus embryos is amplified in presumptive muscle as a delayed response to mesoderm induction.

@article{Harvey1991WidespreadEO,
  title={Widespread expression of MyoD genes in Xenopus embryos is amplified in presumptive muscle as a delayed response to mesoderm induction.},
  author={Richard P. Harvey},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 20},
  pages={9198-202}
}
  • Richard P. Harvey
  • Published 1991 in
    Proceedings of the National Academy of Sciences…
The MyoD gene codes for an important regulatory factor in skeletal myogenesis. To explore the relationship between mesoderm induction in Xenopus embryos and expression of MyoD, I have monitored MyoD mRNA levels in normal embryos and cultured explants by RNase protection. Transcription from the two Xenopus MyoD gene copies is activated weakly across the whole embryo at the midblastula transition, and this activation occurs in the absence of mesoderm induction. In response to induction this basal… CONTINUE READING

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