Widespread decay of vitamin-related pathways: coincidence or consequence?

  title={Widespread decay of vitamin-related pathways: coincidence or consequence?},
  author={Katherine Emma Helliwell and Glen L. Wheeler and Alison G Smith},
  journal={Trends in genetics : TIG},
  volume={29 8},
The advent of modern genomics has provided an unparalleled opportunity to consider the gene complement of an organism, and scrutinize metabolic pathways that are no longer active. This approach has led to an increasing number of reports of vitamin-associated pathway deterioration, with many indicating that independent gene-loss events of one or a few key genes have led to vitamin auxotrophy. Nonfunctional unitary pseudogenes belonging to these pathways are found in several species… CONTINUE READING
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