Widespread Demyelination in the Cerebellar Cortex in Multiple Sclerosis

@article{Kutzelnigg2007WidespreadDI,
  title={Widespread Demyelination in the Cerebellar Cortex in Multiple Sclerosis},
  author={Alexandra Kutzelnigg and Jens C. Faber‐Rod and Jan Bauer and Claudia F. Lucchinetti and Per S. S{\o}rensen and Henning Laursen and Christine Stadelmann and Wolfgang Br{\"u}ck and Helmut Rauschka and Manfred Schmidbauer and Hans Lassmann},
  journal={Brain Pathology},
  year={2007},
  volume={17}
}
Neocortical demyelination in the forebrain has recently been identified as an important pathological feature of multiple sclerosis (MS). Here we describe that the cerebellar cortex is a major predilection site for demyelination, in particular in patients with primary and secondary progressive MS. In these patients, on average, 38.7% of cerebellar cortical area is affected, reaching in extreme examples up to 92%. Cerebellar cortical demyelination occurs mainly in a band‐like manner, affecting… 
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