Wide versus narrow excision margins for high-risk, primary cutaneous melanomas: long-term follow-up of survival in a randomised trial

@inproceedings{Hayes2016WideVN,
  title={Wide versus narrow excision margins for high-risk, primary cutaneous melanomas: long-term follow-up of survival in a randomised trial},
  author={Andrew J. Hayes and Lauren J. Maynard and Gillian Coombes and Julia A. Newton-Bishop and Michael J. Timmons and Martin G. Cook and Jeffrey M Theaker and Judith Margaret Bliss and Joseph Meirion Thomas},
  booktitle={The Lancet. Oncology},
  year={2016}
}
BACKGROUND The necessary margin of excision for cutaneous melanomas greater than 2 mm in thickness is controversial. At a median follow-up of 5 years, findings from our previously published randomised trial of narrow (1 cm) versus wide (3 cm) excision margins in patients with thick cutaneous melanomas showed that narrow margins were associated with an increased frequency of locoregional relapse, but no significant difference in overall survival was apparent. We now report a long-term survival… CONTINUE READING
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