Wide dynamic range phase-sensitive surface plasmon resonance biosensor based on measuring the modulation harmonics.

Abstract

In this study, a novel phase-sensitive surface plasmon resonance (SPR) setup, based on temporal modulation of a pumping beam by a photoelastic modulator, and subsequent extraction of phase information at the second and the third harmonics of the modulation frequency, has been developed to study biomolecular interactions on SPR-supporting gold. We… (More)

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Cite this paper

@article{Law2007WideDR, title={Wide dynamic range phase-sensitive surface plasmon resonance biosensor based on measuring the modulation harmonics.}, author={W. R. Law and Przemyslaw P. Markowicz and Ken-Tye Yong and Indrajit Roy and Alexander A Baev and Sergiy Patskovsky and Andrei V. Kabashin and Ho Pui Ho and Paras N. Prasad}, journal={Biosensors & bioelectronics}, year={2007}, volume={23 5}, pages={627-32} }