Wide-angle X-ray scattering as a probe for insulin denaturation.

Abstract

Wide-angle X-ray scattering (WAXS) from lyophilized protein is characterized by the presence of two relatively broad scattering peaks that are linked to protein structure. This work is concerned with the possibility of utilizing these peaks in the probing of the unfolding and breakdown of insulin. Native insulin is subject to thermal denaturation in the… (More)
DOI: 10.1016/j.ijbiomac.2010.03.011

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