Wide-angle X-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment.

@article{Cornwell1994WideangleXD,
  title={Wide-angle X-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment.},
  author={Philip Cornwell and Brian W. Barry and C P Stoddart and Joke A. Bouwstra},
  journal={The Journal of pharmacy and pharmacology},
  year={1994},
  volume={46 12},
  pages={938-50}
}
Wide-angle X-ray-diffraction experiments were used to investigate the molecular organization of barrier components of human stratum corneum. Diffraction lines related to the side-by-side lipid packing arrangements in the intercellular bilayers were identified as were patterns arising from secondary protein structures in intracellular keratin. Reflections were also identified which may be produced by proteins in the corneocyte envelopes. The effects of hydration on stratum corneum structure were… CONTINUE READING