Why switch from warfarin to NOACs?
@article{Verdecchia2016WhySF, title={Why switch from warfarin to NOACs?}, author={Paolo Verdecchia and Fabio Angeli and Adolfo Aita and Claudia Bartolini and Gianpaolo Reboldi}, journal={Internal and Emergency Medicine}, year={2016}, volume={11}, pages={289-293} }
Several patients with non-valvular atrial fibrillation treated with warfarin or other vitamin-K antagonists (VKA) might benefit from switching to an oral non vitamin-K antagonist anticoagulant (NOAC). In the absence of randomised comparative trials of switching to NOACs versus maintaining VKA treatment, several considerations argue in favour of a switching strategy. First, there is conclusive evidence that haemorrhagic strokes and intracranial bleedings are much fewer in number with NOACs than…
43 Citations
Changing trends in the use of novel oral anticoagulants and warfarin for treating non-valvular atrial fibrillation
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Changing trends in treatment with anticoagulants for patients with non-valvular atrial fibrillation observed within less than two years provide important information to healthcare services to estimate future pharmaco-economic costs for such treatments.
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Evidence thus far indicates that rivaroxaban is superior to warfarin and similar to dabigatran, apixaban and edoxaban for the prevention of stroke or systemic embolism in patients with nonvalvular atrial fibrillation, although rivroxaban may be associated with an elevated bleeding risk compared with other DOACs.
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- MedicineJournal of Cardiology and Cardiovascular Sciences
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- 2018
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- Medicine, BiologySwiss medical weekly
- 2017
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The appropriate antithrombotic therapy when balancing the effectiveness and the risk in different circumstance of concurrence of VTE and CHD is discussed, such as combining anticoagulation therapy, dual antiplatelet therapy (DAPT), triple antithROMbotic Therapy (TAT), thrombolytic therapy and extending therapy, in order to provide safe, standard and effective therapeutic schemes for the clinical management of these patients.
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