• Corpus ID: 249017594

Why strengthening gap junctions may hinder action potential propagation

@inproceedings{Krull2022WhySG,
  title={Why strengthening gap junctions may hinder action potential propagation},
  author={Erin Munro Krull and Christoph Borgers},
  year={2022}
}
. Gap junctions are channels in cell membranes allowing ions to pass directly between cells. They connect cells throughout the body, including heart myocytes, neurons, and astrocytes. Propagation mediated by gap junctions can be passive or active . In passive propagation, the mem- brane potential of one cell influences that of neighboring cells without triggering action potentials (APs). In active propagation, an AP in one cell triggers APs in neighboring cells; this occurs in cardiac tissue and… 

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