Why repetitive DNA is essential to genome function

  title={Why repetitive DNA is essential to genome function},
  author={James A. Shapiro and Richard von Sternberg},
  journal={Biological Reviews},
There are clear theoretical reasons and many well‐documented examples which show that repetitive DNA is essential for genome function. Generic repeated signals in the DNA are necessary to format expression of unique coding sequence files and to organise additional functions essential for genome replication and accurate transmission to progeny cells. Repetitive DNA sequence elements are also fundamental to the cooperative molecular interactions forming nucleoprotein complexes. Here, we review… 

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  • 2002
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  • 1999
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