Why prokaryotes have pangenomes

@article{McInerney2017WhyPH,
  title={Why prokaryotes have pangenomes},
  author={James O. McInerney and Alan McNally and Mary J. O’Connell},
  journal={Nature Microbiology},
  year={2017},
  volume={2}
}
The existence of large amounts of within-species genome content variability is puzzling. Population genetics tells us that fitness effects of new variants—either deleterious, neutral or advantageous—combined with the long-term effective population size of the species determines the likelihood of a new variant being removed, spreading to fixation or remaining polymorphic. Consequently, we expect that selection and drift will reduce genetic variation, which makes large amounts of gene content… 

Selection-based model of prokaryote pangenomes

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Reply to ‘The population genetics of pangenomes’

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A non-adaptive demographic mechanism for genome expansion in Streptomyces

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