Why microscopy will remain a cornerstone of surgical pathology

  title={Why microscopy will remain a cornerstone of surgical pathology},
  author={Juan Rosai},
  journal={Laboratory Investigation},
  • J. Rosai
  • Published 2 April 2007
  • Medicine
  • Laboratory Investigation
Recent years have seen increasing predictions of the demise of conventional microscopy in patient care and investigative medicine. However, these predictions fail to recognize the power of morphologic analysis by a skilled observer. The amount of information that can be obtained from a simple H&E slide represents a windfall in terms of data quality, quantity and cost when compared to any other available technique. Moreover, the value of such interpretation is irreplaceable as we develop newer… 

The evolving landscape of Anatomic Pathology.

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The process that produces digitised sections from a tissue specimen is summarised in order to understand the peculiarity of data, associated artefacts and possible ways to minimise them and the trends and challenges that the field is facing are identified.

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  • Y. Kang
  • Medicine
    Clinical endoscopy
  • 2014
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  • J. Rosai
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    The American journal of pathology
  • 1997
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  • T. Giordano
  • Medicine
    The American journal of surgical pathology
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  • J. Cameselle-TeijeiroJ. Chan
  • Medicine, Biology
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • 1999
Four cases of an unusual sporadic thyroid tumor that shares the morphologic features of a distinctive follicular cell neoplasm previously proposed as a feasible indicator of familial adenomatous polyposis are described, with the behavior of this variant seems to be similar to that of conventional papillary carcinoma.