Why is the world so poorly prepared for a pandemic of hypervirulent avian influenza?

  title={Why is the world so poorly prepared for a pandemic of hypervirulent avian influenza?},
  author={Olav Albert Christophersen and Anna Haug},
  journal={Microbial Ecology in Health and Disease},
  pages={113 - 132}
The world is now extremely poorly prepared to counter a possible pandemic of hypervirulent H5N1 influenza. Most countries are planning for nothing worse than the Spanish flu pandemic. It may be possible that this can in large measure be explained as a consequence of an epidemic of wishful thinking, which may already have infected the health authorities (and parts of the scientific community as well) in most countries in the world. However, it may also be possible that it can have happened as a… 
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[The next pandemic?].
  • L. Garrett
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    Salud publica de Mexico
  • 2006
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