Why is coeliac disease endemic in the people of the Sahara?

  title={Why is coeliac disease endemic in the people of the Sahara?},
  author={Carlo Catassi and I M Ratsch and Lenora Gandolfi and Riccardo Pratesi and Elisabetta Fabiani and Ramzi El Asmar and Maria Frijia and Italo Bearzi and L Vizzoni},
  journal={The Lancet},

The burden of celiac disease and the value of having it diagnosed

A small number of patients diagnosed with celiac disease have shown an intolerance to gluten that is similar to that of a food allergy, and these patients are referred to a gluten-free clinic for further studies.

Systematic review: worldwide variation in the frequency of coeliac disease and changes over time

Coeliac disease (CD), originally thought to be largely confined to Northern Europe and Australasia and uncommon in North America and the Middle East, is now recognised to be equally common in all

World Gastroenterology Organisation global guidelines on celiac disease.

This poster discusses the epidemiology and management of celiac disease, a chronic, immunologically determined form of enteropathy affecting the small intestine in genetically predisposed children and adults.

Towards explaining the Swedish epidemic of celiac disease : an epidemiological approach

A large number of cases of celiac disease in Sweden are undiagnosed, and the vast majority of cases are due to ignorance of the disease's symptoms.

Celiac disease in the developing world.

Celiac disease and Infections

A small number of patients with a history of celiac disease and/or high-risk of gluten-related illnesses are diagnosed with atypical central giant cell granuloma, which is a leading cause of death in people with Celiac disease.

New developments in childhood Celiac Disease

This review addresses new developments in CD with respect to pediatric patients and emphasizes the need for awareness among health-care professionals.

Epidemiology of Celiac Disease.

The international face of coeliac disease.

  • R. SharafE. VernaP. Green
  • Medicine
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2004



Anti-reticulin antibodies: useful adjunct to histopathology in diagnosing celiac disease, especially in a developing country.

A positive ARA assay with an initial subtotal villous atrophy was seen to always suggest CD, and these together would provide a useful basis for instituting gluten-free diets in suspected cases of CD rather than histological findings alone.

Chronic diarrhea and malnutrition--histology of the small intestinal lesion.

The jejunal lesion in Gambian children with chronic diarrhea-malnutrition syndrome is consistent with an intestinal reaction to some environmental antigen of the cell-mediated type, strengthened by the expression of major histocompatibility class 2D locus alloantigens on crypt epithelial cells in the absence of gut-reactive autoantibodies.

Expression of receptors for enterotoxigenic Escherichia coli during enterocytic differentiation of human polarized intestinal epithelial cells in culture

Both in HT-29 cells (HT-29 Glc-/+) and in Caco-2 cells cultured under standard conditions, ETEC CFA receptors develop as a function of day in culture, indicating that the expression of the ETECCFA receptors was a growth-related event.