Why is ALS so Difficult to Treat?

  • John R. Turnbull
  • Published 2014 in
    The Canadian journal of neurological sciences. Le…


Amyotrophic lateral sclerosis (ALS) is proving intractable. Difficulties in pre-clinical studies contribute in small measure to this futility, but the chief reason for failure is an inadequate understanding of disease pathogenesis. Many acquired and inherited processes have been advanced as potential causes of ALS but, while they may predispose to disease… (More)


4 Figures and Tables