Why have studies of tailored anti-platelet therapy failed so far?

@article{SillerMatula2013WhyHS,
  title={Why have studies of tailored anti-platelet therapy failed so far?},
  author={Jolanta Maria Siller-Matula and Bernd Jilma},
  journal={Thrombosis and haemostasis},
  year={2013},
  volume={110 4},
  pages={628-31}
}
Published data linking clopidogrel non-responsiveness to adverse ischaemic events lead to the suggestion that the magnitude of platelet inhibition by clopidogrel can be monitored and individually adjusted. This has been tested in randomised clinical trials (ARCTIC, GRAVITAS and TRIGGER-PCI), but despite reducing platelet reactivity, a strategy of therapy… CONTINUE READING