Why does the north-south gradient of incidence of multiple sclerosis seem to have disappeared on the northern hemisphere?

@article{KochHenriksen2011WhyDT,
  title={Why does the north-south gradient of incidence of multiple sclerosis seem to have disappeared on the northern hemisphere?},
  author={Nils J Koch-Henriksen and Per Soelberg Sorensen},
  journal={Journal of the neurological sciences},
  year={2011},
  volume={311 1-2},
  pages={58-63}
}
The traditional view, based on numerous early studies and reviews, is that MS is particularly prevalent in temperate zones both on the northern and southern hemisphere. This uneven distribution of MS can be attributed to differences in genes and environment and their interaction. Diagnostic accuracy and case ascertainment are sources of error and have their shares in the geographical and temporal variations, and improvements in diagnostic accuracy and case ascertainment influence incidence- and… CONTINUE READING
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