Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing.

@article{Maxwell2016WhyDE,
  title={Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing.},
  author={Susan M. Maxwell and P. C. Colls and Brooke Hodes-Wertz and D Mcculloh and C. Nadeane McCaffrey and Dagan Wells and Santiago Munn{\'e} and James A. Grifo},
  journal={Fertility and sterility},
  year={2016},
  volume={106 6},
  pages={
          1414-1419.e5
        }
}
OBJECTIVE To determine whether undetected aneuploidy contributes to pregnancy loss after transfer of euploid embryos that have undergone array comparative genomic hybridization (aCGH). DESIGN Case-control study. SETTING University-based fertility center. PATIENT(S) Cases included 38 patients who underwent frozen euploid ET as determined by aCGH, resulting in miscarriage. Controls included 38 patients who underwent frozen euploid ET as determined by aCGH, resulting in a live birth… CONTINUE READING
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