Why do class I MHC molecules bind smaller peptides than class II MHC molecules?

Abstract

This article attempts to assemble theoretical-teleological argument to explore possible answers to the question of why class I MHC molecules bind smaller peptides than class II MHC molecules and the associated question of why the size of peptides binding to class I molecules is approaching the limit of the self-non-self discrimination. I propose that the… (More)

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Cite this paper

@article{Blanden1995WhyDC, title={Why do class I MHC molecules bind smaller peptides than class II MHC molecules?}, author={Robert V. Blanden}, journal={Immunology and cell biology}, year={1995}, volume={73 1}, pages={95-7} }