Why do c-type cytochromes exist?

  title={Why do c-type cytochromes exist?},
  author={P. M. Wood},
  journal={FEBS letters},
  volume={164 2},
The hypothesis presented is that the different classes of c-type cytochrome originated as proteins located in the bacterial periplasmic space, or on the periplasmic side of the cytoplasmic membrane. In these locations, covalent bonds between haem and protein prevented the haem from being lost to the surrounding medium. Subsequent evolution has led to internal location of c-type cytochromes in eucaryotes and cyanobacteria. The covalent links have been retained because of their structural role; a… CONTINUE READING

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Cytochromes c

Springer Series in Molecular Biology • 1987

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