Why do African Americans get more colon cancer than Native Africans?

@article{Okeefe2007WhyDA,
  title={Why do African Americans get more colon cancer than Native Africans?},
  author={Stephen J D O'keefe and Dan Chung and Nevine Mahmoud and Antonia Rogado Sepulveda and Mashudu Manafe and Judith E Arch and Haytham Adada and Tian van der Merwe},
  journal={The Journal of nutrition},
  year={2007},
  volume={137 1 Suppl},
  pages={175S-182S}
}
The incidence of colorectal cancer (CRC) is dramatically higher in African Americans (AAs) than in Native Africans (NAs) (60:100,000 vs. <1:100,000) and slightly higher than in Caucasian Americans (CAs). To explore whether the difference could be explained by interactions between diet and colonic bacterial flora, we compared randomly selected samples of healthy 50- to 65-y-old AAs (n = 17) with NAs (n = 18) and CAs (n = 17). Diet was measured by 3-d recall, and colonic metabolism by breath… CONTINUE READING
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